Ayotunde Adesugba attended Brockley Primary School and Collingwood Girls’ Secondary School both in the United Kingdom and Methodist Girls’ High School Yaba, Lagos where she earned her West African School Certificate (WASC). She attended Queens’ College Onikan, Lagos for her Higher Certificate (HSC) before proceeding to the University of Ife, Ile Ife, (now Obafemi Awolowo University), where she graduated with a BA Hons. in English in 1979.
Upon completing her National Youth Service, she went back to the University of Ife where she bagged a Masters Degree in Literature in English in 1982.
She joined the Federal Ministry of Information where she rose steadily and served in various capacities, including Press Attach’e and Head of the Information and Cultural Service Centre, Embassy of Nigeria, Paris, France from 2001 to 2003 and Information Attach’e in the Nigeria Information Service Centre, Embassy of Nigeria, Abijdan, Cote d’ Ivoire from 1992 to 1995.
In 2006,during the outbreak of Avian Influenza in Nigeria, she was posted to Head the Information Desk of the National Avian and Pandemic Influenza Prevention & Control Centre, Abuja.
She was Director Information in the State House Abuja from 2012 to 2014, before she was posted to the Federal Ministry of Health where she served as Director Press & Public Relations until her current appointment as the Permanent Secretary in November 2015.
She is married and blessed with children.